Matt Dominguez hit a three-run homer, Tyler Greene added a solo shot and the Houston Astros slowed Cincinnati's run to the NL Central title with a 5-1 win over the Reds on Sunday.
Edgar Gonzalez allowed two hits and one run in five innings against the Reds, who came in with a magic number of 14 for eliminating second-place St. Louis. Gonzalez (2-0) walked one and struck out six, and the Astros limited Cincinnati to five hits overall while winning a road series for the first time since early June against the White Sox.
The Reds, who also lost two of three against Philadelphia in the first series of their nine-game homestand, have lost back-to-back series for the first time since being swept by Cleveland June 18-20 and losing two of three to Minnesota June 22-24.
Houston relievers Wesley Wright , Mickey Storey and Wilton Lopez combined for eight strikeouts over four shutout innings.
After going 11-0 in his first 13 afternoon starts this season, Johnny Cueto has struggled in his last two. He gave up eight hits and four runs in seven innings of a 4-2 loss to Philadelphia on Labor Day and followed up by getting knocked around for four runs on nine hits with six strikeouts in four innings on Sunday.
Cueto (17-8) matched his season low in innings while losing a second consecutive start for the first time since July 3.
The last-place Astros scored a first-inning run for the third time in the three-game series. Jimmy Paredes , Brian Bogusevic and Brett Wallace each singled to load the bases with nobody out, setting up Fernando Martinez 's sacrifice fly.
Houston took command with a two-out, fourth-inning rally sparked by Wallace's single to right. After Martinez walked, Dominguez drove Cueto's 1-0 pitch 368 feet into the left field seats for his third home run of the season and second three-run shot of the series against one of Cincinnati's more dominant pitchers. Dominguez's three-run homer off Aroldis Chapman on Friday gave Houston a 5-3 win.
The Reds got on the board in the fourth. Joey Votto walked with one out and scored on Jay Bruce 's triple to center field. The Astros got that run back on Green's 10th homer of the season, a 378-foot shot into the right field seats off of Tony Cingrani with one out in the sixth inning.